References Main Reference: Willy Wriggers. Conventions and Workflows for Using Situs. Acta Cryst. D, 2012, Vol. 68, pp. 344-351. Thematically Specialized References: Flexible Fitting to Medium Resolution Maps: Julio Kovacs, Vitold Galkin, and Willy Wriggers. Accurate Flexible Refinement of Atomic Models Against Medium-Resolution Cryo-EM Maps Using Damped Dynamics. BMC Struct Biol., 2018, Vol 18 Nr. 12. Validation: Willy Wriggers and Jing He. Numerical Geometry of Map and Model Assessment. J. Struct. Biol., 2015, Vol. 192, pp. 255-261. First decade of Situs history: Willy Wriggers. Using Situs for the Integration of Multi-Resolution Structures. Biophysical Reviews, 2010, Vol. 2, pp. 21-27. Vector quantization method: Willy Wriggers, Ronald A. Milligan, Klaus Schulten, and J. Andrew McCammon. Self-Organizing Neural Networks Bridge the Biomolecular Resolution Gap. J. Molecular Biology, 1998, Vol. 284, pp. 1247-1254. Correlation-based docking: Pablo Chacón and Willy Wriggers. Multi-Resolution Contour-Based Fitting of Macromolecular Structures. J. Mol. Biol., 2002, Vol 317, pp. 375-384. Application to SAXS: Willy Wriggers and Pablo Chacón. Using Situs for the Registration of Protein Structures with Low-Resolution Bead Models from X-ray Solution Scattering. J. Appl. Cryst., 2001, Vol. 34, pp. 773-776. Map editing, discrepancy mapping, review of docking algorithms: Willy Wriggers and Pablo Chacón. Modeling Tricks and Fitting Techniques for Multi-Resolution Structures. Structure, 2001, Vol. 9, pp. 779-788. Point cloud matching: Stefan Birmanns and Willy Wriggers. Multi-Resolution Anchor-Point Registration of Biomolecular Assemblies and Their Components. J. Struct. Biol. 2007, Vol. 157, pp. 271-280. Low-resolution flexible fitting: Mirabela Rusu, Stefan Birmanns, and Willy Wriggers. Biomolecular Pleiomorphism Probed by Spatial Interpolation of Coarse Models. Bioinformatics, 2008, Vol. 24, pp. 2460-2466. Simultaneous multi-fragment fitting with collage: Stefan Birmanns, Mirabela Rusu, and Willy Wriggers. Using Sculptor and Situs for Simultaneous Assembly of Atomic Components into Low-Resolution Shapes. J. Struct. Biol., Vol. 173, pp. 428–435, 2011. Histogram density matching with volhist: Willy Wriggers, Lorenzo Alamo, and Raúl Padrón. Matching Structural Densities from Different Biophysical Origins with Gain and Bias. J. Struct. Biol., Vol. 173, pp. 445–450, 2011. Alpha-helix detection with voltrac: Mirabela Rusu and Willy Wriggers. Evolutionary Bidirectional Expansion for the Tracing of Alpha Helices in Cryo-Electron Microscopy Reconstructions. J. Struct. Biol., Vol. 177, pp. 410-419, 2012. Tomography filament detection with voltrac: Mirabela Rusu, Zbigniew Starosolski, Manuel Wahle, Alexander Rigort, and Willy Wriggers. Automated tracing of filaments in 3D electron tomography reconstructions using Sculptor and Situs. J. Struct. Biol., Vol. 178, pp. 121-128, 2012. Denoising with volfltr: Zbigniew Starosolski, Marek Szczepanski, Manuel Wahle, Mirabela Rusu, and Willy Wriggers. Developing a Denoising Filter for Electron Microscopy and Tomography Data in the Cloud. Biophysical Reviews, Vol. 4, pp. 223-229, 2012. Return to the front page .